Depolarization Induced Suppression of Excitation and the Emergence of Ultraslow Rhythms in Neural Networks

Author(s): J. Hlinka and S. Coombes
Ultraslow fluctuations (0.01–0.1 Hz) are a feature of intrinsic brain activity of as yet unclear origin. We propose a candidate mechanism based on retrograde endocannabinoid signaling in a synaptically coupled network of excitatory neurons. This is known to cause depolarization-induced suppressio…

[Phys. Rev. Lett. 104, 068101] Published Mon Feb 08, 2010